ASTCT Pharmacy SIG Journal Club - September 2023

The September 2023 Pharmacy SIG Journal Club aired on Wednesday, September 27, 2023 at 2 pm CDT/3 pm EDT. This webinar consists of two, 30-minute journal club presentations, which include 20 minutes for the presentation and 10 minutes for discussion and a Q&A session. In the September Journal Club session, Drs. Knauss and Zodrow presented on two articles related to (a) post-transplant cyclophosphamide for graft-versus-disease (GVHD) prophylaxis for patients undergoing allogeneic HCT with reduced intensity conditioning and (b) abatacept for steroid-refractory chronic GVHD. This session is intended for pharmacists and other members of the health care team who are involved in managing patients undergoing allogeneic stem cell transplant.

Presenters & Articles

Gionna Knauss, PharmD

PGY-2 Pharmacy Resident

Geisinger Medical Center

Article: Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis


Rebecca Zodrow, PharmD

PGY-2 Pharmacy Resident

University of Kansas

Article: Phase 2 clinical trial evaluating abatacept in patients with steroid-refractory chronic graft-versus-host disease

Session Learning Objectives:

Upon completion of the activity, participants should be able to:

  1. Review graft-versus-host disease (GVHD) prophylaxis strategies for allogenic hematopoietic stem cell transplant
  2. Compare GVHD outcomes for patients receiving Post-Transplant Cyclophosphamide-tacrolimus-mycophenolate mofetil compared to standard prophylaxis methotrexate-tacrolimus
  3. Evaluate the efficacy of abatacept in patients with steroid-refractory chronic graft-versus-host-disease (cGVHD)
  4. Analyze the safety and tolerability of abatacept in patients with steroid-refractory cGVHD
  5. Discuss the clinical role of abatacept in patients with steroid-refractory cGVHD


This activity is jointly provided by The France Foundation and American Society for Transplantation and Cellular Therapy (ASTCT).

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In support of improving patient care, this activity has been planned and implemented by The France Foundation and American Society for Transplantation and Cellular Therapy (ASTCT). The France Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.





This knowledge-based activity, UAN JA0007204-9999-23-038-L01-P, qualifies for 1.0 contact hours (0.10 CEUs) of continuing pharmacy education credit. Please submit all evaluations and credit requests no later than 30days after you complete this activity to ensure your credit fulfillment, as CE credit cannot be awarded past 60 days from the activity date. Your CE credits will be electronically submitted to the NABP upon successful completion of the activity. Pharmacists with questions can contact NABP customer service (

All other healthcare professionals completing this course will be issued a statement of participation.

The full CE information for this session, including presenter disclosures and accreditation information, can be found here.


Webinar Recording
Open to view video.
Open to view video.
Speaker Slides
Open to download resource.
Open to download resource.