Join our expert panelists in this roundtable webinar to discuss unmet needs in graft-versus-host disease (GVHD). In this webinar, our moderator Dr. Noa Holtzman (National Cancer Institute of NIH) leads a discussion with expert panelists Dr. Betty Hamilton (Cleveland Clinic) and Dr. Shernan Holtan (University of Minnesota) about the recent advancements and anticipated future developments in GVHD. Topics discussed include: an overview of the current state of GVHD, advancements in GVHD prevention and treatment, how to better care for GVHD patients, and future changes in the field. This webinar is supported by the GVHD Alliance in honor of the first ever GVHD Day on Friday, February 17, at the 2023 Tandem Meetings of ASTCT & CIBMTR. The GVHD Alliance and GVHD Day are supported by Sanofi.

ASTCT January Journal Club Session

This journal club aired live on January 18, 2022, as a part of the expanded ASTCT Journal Club. This webinar consisted of two, 30-minute journal club presentations, which included 20 min for presentation and 10 min for discussion/Q and A.

Presenters & Articles

Dr. Ahsan Kamal, University of Arizona

Posttransplant cyclophosphamide for prevention of graft-versus-host disease: results of the prospective randomized HOVON-96 trial

Dr. Ronald Funk, Emory University

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

This is the recording and slides of the session presented live at the 2022 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Friday, November 18, 2022. 

Topics include:

• CAR T vs ASCT in NHL
• Treatment Sequencing, including 2^nd CAR (myeloma)
• New Technologies
• Off the Shelf CAR
• Building Trial Efficiencies, Optimal Trial Design, Building Efficiencies

Session Chairs:

• Miguel-Angel Perales (Memorial Sloan Kettering Cancer Center)
• Catherine Bollard (Children’s National Hospital)

Speakers: 

• Miguel-Angel Perales (Memorial Sloan Kettering Cancer Center)
• Damian Green (Fred Hutch)
• Aude Chapuis (Fred Hutch)
• Carlos Ramos (Baylor)
• JoyceLynn Palmer (City of Hope) 

Panelists:

• Nina Shah (AstraZeneca)
  

This is the recording and slides of the session presented live at the 2022 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Friday, November 18, 2022. 

Topics include:

• IFNy pathway and CAR T-cell toxicities
• IL-1 targeting with CRS and ICANS
• HLH-like toxicities and CAR T-cells
• CNS-tumor targeting of CAR T-cells
• ASH CAR T Toxicity Project Update 

Session Chairs:

• Nirali Shah (NCI)
• Amy Moskop (MCW -CIBMTR) 

Speakers: 

• Marcela Maus (MGH)
• Jae Park (MSKCC)
• Nirali Shah (NCI)
• Robbie Majzner (Stanford)
• Fabiana Perna (Indiana University) 

Panelists:

• Noelle Frey (University of Pennsylvania) 

This is the recording and slides of the session presented live at the 2022 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Thursday, November 17, 2022. 

Topics include:

• Background and Update on 80/20
• FDA Programs: The Purpose and Current Processes for REMS, EAPs, BLA 
• EAPs in CART Therapy: Site Challenges and Opportunities for Improvement 
• REMS &Education in CART Therapy: Site Challenges and Opportunities for Improvement 
• BLA and Audits: Site Challenges and Opportunities for Improvement 

Session Chairs:

• Noelle Frey (University of Pennsylvania)
• Partow Kebriaei (MD Anderson Cancer Center) 

Speakers: 

• Fred Locke (Moffitt Cancer Center)
• Peter Marks (FDA)
• Matthew Frigault (MGH)
• Sarah Nikiforow (Dana Farber Cancer Institute)
• Rebecca Gardner (Seattle Children’s Hospital) 

Panelists:

• Robb Richards (University of Pennsylvania)
• Madan Jagasia (Iovance)

This is the recording and slides of the session presented live at the 2022 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Thursday, November 17, 2022. 

Topics include:

• Center Specific Outcomes from a Payers Perspective 
• Center Specific Outcomes from a Center Perspective 
• Center Specific Outcomes from a Data Collection/Analysis Perspective
• Race & Ethnic Disparities in Access and Outcomes: An Update on ASTCT/NMDP Access Initiative 

Session Chairs:

• Jeff Auletta (NMDP)
• Anthony Bonagura (Optum) 

Speakers: 

• Jeff Auletta (NMDP)
• Anthony Bonagura (Optum) 
• Navneet Majhail (Sarah Cannon)
• Patty Steinert (CIBMTR)

Panelists:

• Marcelo Pasquini (CIBMTR)
• Stephanie Farnia (Nimmit Consulting)

These are the recordings and slides of the four sessions from the live virtual event the 2022 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy, hosted by ASTCT™, the CIBMTR® and the National Marrow Donor Program®(NMDP)/Be The Match®. This live event took place on November 17 and 18, 2022. This two-day, virtual workshop offered providers, payers, government agencies, and industry involved in the field of cell and gene therapy increased educational and advocacy opportunities. This new workshop featured educational sessions bridging the gap among stakeholders, and identify ongoing needs and opportunities in the field for advocacy, measurement of value and impact, and sustainability.

Purchase this package to get access to all four sessions at a discounted rate! Individuals who registered to attend this event live are eligible to receive access to these recordings free of charge. Please email info@astct.org to receive your discount.

Please join us for the ASTCT Pharmacy SIG Early Career Search Initiative Panel on Wednesday, November 16 at 2 pm CDT/ 3pm EST.  This live session will feature a panel of pharmacists in traditional and non-traditional oncology pharmacy roles discussing their respective career paths. 

The goal of this session is to help incoming and new practitioners identify strategies and guidance to enhance their career search by engaging with a panel of pharmacists in traditional and non-traditional roles. Audience questions will be welcomed during the Q&A portion of the session. 

This event is open to all healthcare professionals who are members and non-members of ASTCT. 

If you have any questions for our panelists, please submit them to info@astct.org with the subject line, 'ASTCT Pharmacy SIG Early Career Search Initiative Q&A.'

We hope to see you on November 16!

Panelists: 

• Kelley Carlstrom, PharmD, BCOP - Founder ELO Collaborative
• Amber Clemmons PharmD, BCOP, FHOPA - Clinical Professor University of Georgia College of Pharmacy, BMT Clinical Pharmacist at Augusta University Medical Center, PGY2 Oncology Residency Director UGA/AUMC
• LeAnne Kennedy, PharmD, BCOP, CPP. FHOPA - Atrium Health Wake Forest Baptist PGY2 Oncology Residency Program Director, Pharmacy Clinical Specialist Stem Cell Transplant and Cellular Therapy, HOPA President-Elect
• Jill Kolesar, PharmD - Markey Cancer Center Director of the Precision Medicine Center, Co-Chair of the Molecular Tumor Board, and the Co-Leader of the Translational Oncology Program, Graduate Faculty at University of Kentucky School of Pharmacy
• Julianna Roddy-McLean, PharmD, BCOP - Hematology Regional Medical Scientific Director at Merck

ASTCT October Journal Club Session

This journal club aired live on October 26, 2022, as a part of the expanded ASTCT Journal Club. This webinar consisted of two, 30-minute journal club presentations, which included 20 min for presentation and 10 min for discussion/Q and A.

Presenters & Articles

Dr. Anna Johnson, University of Kentucky

Randomized Phase III BMT CTN Trial of Calcineurin Inhibitor–Free Chronic Graft-Versus-Host Disease Interventions in Myeloablative Hematopoietic Cell Transplantation for Hematologic Malignancies

Dr. Loretta Parker, Emory University

Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant

These are the ASTCT 2022 National Fludarabine Shortage for HCT and CAR T-Cell Recipients: Frequently Asked Questions.

Please complete this optional survey regarding the shortage here.