Management and Prevention of Paramyxoviruses in Hematopoietic Cell Transplantation Recipients
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This session covered the latest guidelines for managing respiratory syncytial virus (RSV) and other paramyxoviruses, focusing on epidemiology, clinical diagnosis, prophylaxis, and treatment strategies. Experts will discuss special considerations for pediatric, cord blood, haploidentical, and T cell-depleted HCT patients, as well as chimeric antigen receptor T cell therapy recipients. Review the recently published guidelines here.
Learning Objectives:
- Analyze the epidemiological patterns and risk factors of paramyxovirus infections in hematopoietic cell transplantation (HCT) recipients.
- Evaluate and differentiate the key clinical features for the paramyxoviruses hMPV and PIV in HCT patients.
- Apply current prophylaxis and treatment strategies for paramyxovirus infections in HCT recipients, comparing their effectiveness and potential outcomes.
- Synthesize special considerations for paramyxovirus management in specific HCT patient populations, integrating various factors that influence treatment decisions
Panelists:
- Marjorie Vieira Batista, MD, TID, PhD, ACCamargo Cancer Center
- Alpana Waghmare, MD, Department of Pediatrics, University of Washington School of Medicine
Moderators:
- Roy F. Chemaly, MD, MPH, FIDSA, FACP, FESCMID, Department of Infectious Diseases, MD Anderson Cancer Center
- Diego R Hijano, MD, MSc, St. Jude Children's Research
The American Society for Transplantation and Cellular Therapy (ASTCT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
The American Society for Transplantation and Cellular Therapy (ASTCT) designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Financial Disclosures
| Name | Role | Company | Nature of Relationship |
| Marjorie Vieira Batista, MD, PhD | Speaker | Takeda | Speaking and teaching engagements; consulting fees |
| Merck & Co. | Speaking and teaching engagements; consulting fees | ||
| AbbVie | Speaking and teaching engagements; consulting fees | ||
| Johnson & Johnson Innovative Medicine | Speaking and teaching engagements; honoraria; consulting fees | ||
| Alpana Waghmare, MD | Speaker | Pfizer | Research funding (Principal Investigator/Researcher) |
| Merck & Co. | Research funding; consulting fees | ||
| Ansun | Research funding | ||
| Gilead | Advisory Committee member; consulting fees | ||
| AstraZeneca | Consultant; consulting fees | ||
| Diego Hijano, MD, MSc | Moderator | Pfizer | Consultant; consulting fees |
| Roy Chemaly, MD | Moderator | ADMA Biologics | Consultant; advisor; research funding |
| Merck/MSD | Consultant; advisor; research funding | ||
| Takeda | Consultant; research funding | ||
| Shionogi | Advisor | ||
| Eurofins-Viracor | Consultant; research funding | ||
| AiCuris | Consultant; research funding | ||
| Roche/Genentech | Research funding | ||
| Astellas | Consultant | ||
| Pierre Fabre | Consultant | ||
| Gilead | Research funding | ||
| AbbVie | Consultant | ||
| Oxford Immunotec | Consultant | ||
| Karius | Advisor; research funding (terminated 1 year ago) | ||
| Moderna | Consultant | ||
| Ansun Pharmaceuticals | Consultant; research funding |