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The ASTCT Pharmacy SIG November 2023 Journal Club will air on Wednesday, November 29, 2023 at 2 pm CST/3 pm EST.
The ASTCT Pharmacy SIG November 2023 Journal Club will air on Wednesday, November 29, 2023 at 2 pm CST/3 pm EST. This webinar consists of two, 30-minute journal club presentations, which include 20 minutes for the presentation and 10 minutes for discussion and a Q&A session. In the November Journal Club session, Drs. Patel and Gash will present on two articles related to (a) ciltacabtagene autoleucel or standard of care treatment in lenalidomide-refractory multiple myeloma and (b) post-transplant cyclophosphamide, abatacept, and a short course of tacrolimus (CAST) after peripheral blood haploidentical HSCT.
This session is intended for pharmacists and other members of the health care team who are involved in managing patients undergoing CAR T-cell therapy or hematopoietic stem cell transplant.
Presenters & Articles
Shikha P. Patel, PharmD, BCPS
PGY-2 Pharmacy Resident
Mayo Clinic
Article: Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma
Kyle Gash, PharmD
PGY-2 Pharmacy Resident
Moffitt Cancer Center
Session Learning Objectives:
Upon completion of the activity, participants should be able to:
- Review the role of CAR T-cell therapy in relapsed/refractory multiple myeloma
- Describe the mechanism of action of ciltacabtagene autoleucel
- Evaluate the efficacy and safety of ciltacabtagene autoleucel compared to standard regimens in the management of relapsed/refractory multiple myeloma
- Review graft-versus-host disease (GVHD) prophylaxis regimens following haploidentical hematopoietic stem cell transplantation (HCT)
- Analyze the safety and efficacy of post-transplant cyclophosphamide (PTCy), abatacept, and a short course of tacrolimus (CAST) for GVHD prevention
- Discuss the utility of the CAST regimen for GVHD prevention after haploidentical HCT
ACCREDITED PROVIDER
This activity is jointly provided by The France Foundation and American Society for Transplantation and Cellular Therapy (ASTCT).
In support of improving patient care, this activity has been planned and implemented by The France Foundation and American Society for Transplantation and Cellular Therapy (ASTCT). The France Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
CREDIT DESIGNATION
Pharmacists
This knowledge-based activity, UAN JA0007204-9999-23-041-L01-P, qualifies for 1.0 contact hours (0.10 CEUs) of continuing pharmacy education credit. Please submit all evaluations and credit requests no later than 30days after you complete this activity to ensure your credit fulfillment, as CE credit cannot be awarded past 60 days from the activity date. Your CE credits will be electronically submitted to the NABP upon successful completion of the activity. Pharmacists with questions can contact NABP customer service (custserv@nabp.net).
All other healthcare professionals completing this course will be issued a statement of participation.
The full CE information for this session can be found here.
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Contains 10 Product(s)
These are all the recordings and slides of the ten sessions from the live event the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy, hosted by ASTCT™, the CIBMTR® and the National Marrow Donor Program®(NMDP)/Be The Match®. Purchase this package to get access to all ten sessions at a discounted rate!
These are the recordings and slides of the four sessions from the live event the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy, hosted by ASTCT™, the CIBMTR® and the National Marrow Donor Program®(NMDP)/Be The Match®. This live event took place on October 2 and 3, 2023. The two-day, hybrid workshop offered providers, payers, government agencies, and industry involved in the field of cell and gene therapy increased educational and advocacy opportunities. This workshop featured educational sessions bridging the gap among stakeholders, and identify ongoing needs and opportunities in the field for advocacy, measurement of value and impact, and sustainability.
Purchase this package to get access to all ten sessions at a discounted rate! Individuals who registered to attend this event live are eligible to receive access to these recordings free of charge. Please email info@astct.org to receive your discount.
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- Non-member - $80
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Contains 4 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- CAR-T Barriers to Care
- Point of Care Manufacture of CAR T cells
- Point of Care Manufacturing: Enabling affordable and accessible advanced medicines
Session Chair:
- Boro Dropulić, PhD, MBA; Caring Cross
Speakers:
- Armin Ghobadi, MD; Washington University School of Medicine
- Marcos de Lima, MD; The Ohio State University Comprehensive Cancer Center
- Boro Dropulić, PhD, MBA; Caring Cross
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- Non-member - $10
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Contains 4 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- Pearls of Cellular Therapy Manufacturing Logistics
- Clinical Use of Mesenchymal Stem Cells (MSCs) and MSC-Exosomes: Immune Suppression, Regenerative Medicine, and Gene Delivery
- Virus-Specific T Cells
Session Chair:
- Elizabeth Shpall, MD; MD Anderson Cancer Center
Speakers:
- Ray Hornung, MBA, MBCI, CEM, CBCP; NMDP
- Elizabeth Shpall, MD; MD Anderson Cancer Center
- Adrian Gee, PhD; Center for Cell & Gene Therapy, Baylor College of Medicine Houston
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- Non-member - $10
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Contains 4 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- Equity of Access to HCT/ Cell Therapy
- Need to Reduce Business Operations Complexity in Advancing Patients Through Cellular Therapy Treatment
- Developing Tools to Widen Patient Access to Complex Therapies
Session Chair:
- Amy Emmert, MScPH, Dana-Farber Cancer Institute
Speakers:
- Nandita Khera, MD, MPH; Mayo Clinic AZ
- Amy Emmert, MScPH, Dana-Farber Cancer Institute
- Robert Richards, MS, MBA; Penn Medicine
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- Non-member - $10
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Contains 4 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- Bispecifics vs CARs
- Sequencing Bispecific Antibody Therapies and CAR-T cells in Multiple Myeloma
- Future Directions for Solid Tumors
Session Chair:
- Neha Korde, MD; Memorial Sloan Kettering Cancer Center
Speakers:
- Syed Abbas Ali, MD; John Hopkins University
- Neha Korde, MD; Memorial Sloan Kettering Cancer Center
- Roisin O’Cearbhaill, MD; Memorial Sloan Kettering Cancer Center
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- Non-member - $10
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Contains 5 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- Biological Drivers of CAR T Cell Failure
- Patient-Specific Factors Impacting CAR T Cell Efficacy
Session Chair:
- Shannon Maude, MD, PhD; Children's Hospital of Pennsylvania/Perelman School of Medicine at the University of Pennsylvania
Speakers:
- Nathan Singh, MD; Washington University School of Medicine
- Regina Myers, MD; Children's Hospital of Pennsylvania/Perelman School of Medicine at the University of Pennsylvania
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- Non-member - $10
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Contains 5 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Monday, October 2, 2023.
Topics include:
- Building a Cellular Therapy Program: Inpatient & Outpatient
- Building your Program to be Able to Adapt to Solid Tumors
- Is there an Optimal Cell Therapy Service Structure?
Session Chair:
- Sairah Ahmed, MD; MD Anderson Cancer Center
Speakers:
- Krish Patel, MD; Swedish Cancer Institute
- Samer Srour, MB ChB, MS; MD Anderson Cancer Center
- Gunjan Shah, MD, MS; Memorial Sloan Kettering Cancer Center
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- Non-member - $10
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Contains 5 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Tuesday, October 3, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Tuesday, October 3, 2023.
Topics include:
- Allogeneic vs Autologous Therapies and How they Compete
- Alternative Targets: Beyond B-Cell Malignancies
- Allogeneic NK Cell Platform for Cancer Immunotherapy
Session Chair:
- Matthew Frigault, MD; MGH
Speakers:
- Jay Spiegel, MD; University of Miami, Sylvester Comprehensive Cancer Center
- Rayne Rouce, MD; Baylor College of Medicine/Texas Children's Hospital
- Veronika Bachanova, MD, PhD; University of Minnesota
Panelist:
- Elizabeth Shpall, MD; MD Anderson Cancer Center
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Contains 6 Component(s)
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Tuesday, October 3, 2023.
This is the recording and slides of the session presented live at the 2023 AcCELLerate Forum: Creating a Sustainable Ecosystem of Cell and Gene Therapy. The event aired live on Tuesday, October 3, 2023.
Topics include:
- Prevention and Management of Refractory CRS
- Emergent Neurotoxicities
- Immune Effector Cell-associated HLH-like Syndrome
- Immune Effector Cell Associated Hematotoxicity(ICAHT): European Guidelines
Session Chairs:
- Nirali Shah, MD, MHSc; National Cancer Institute
- Kevin McNerney, MD, MSc; Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine
Speakers:
- Michael Jain, MD, PhD; Moffitt Cancer Center
- Bianca Santomasso, MD, PhD; Memorial Sloan Kettering Cancer Center
- Kevin McNerney, MD, MSc; Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine
- Marion Subklewe, MD; University Hospital Munich
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